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RhoA-GTP

Anti-RhoA-GTP Mouse Monoclonal Antibody
5/5

$495.00

Cat.#:  26904

   Size:   30 μl

In Stock

          Product Description          
Anti-RhoAGTP Mouse Monoclonal Antibody
Cat. #:   26904
Size:  30 µL
Gene Symbol:  RHOA
Description:   Anti-RhoA-GTP Mouse Monoclonal Antibody
Background:   Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction.
Immunogen:   Recombinant full length protein of active RhoA
Applications:   IP, IHC and IF (Not applicable for WB since SDS denatures RhoA GTPase)
Published Applications:  IF, IHC; Click for Details –    Part 01     Part 02
Recommended Dilutions:    IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG2b
Purity:   Purified from ascites
Preservative: No
Constituents:  PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-RhoA monoclonal antibody recognizes active RhoA from vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing
Immunoprecipitation/Western blot: IP/WB Analysis of Active RhoA Protein. Purified recombinant RhoA proteins were loaded with GDP (lane 1) or GTPγS (lane 2). These proteins were immunoprecipitated with anti-RhoA-GTP monoclonal antibody (Cat. # 26904). After SDS/PAGE, the membrane filter was probed with anti-RhoA mouse monoclonal antibody (Cat. # 26007).
IHC staining for Ki67, Active RhoA -GTP, YAP1 and Myc in subcutaneous tumour sections Immunofluorescence analysis of the attrey sections was performaned using RhoAGTP mAb as shown in red staining
Immunofluorescence assay of HLMECsi with RhoAGTP mAb, shown as green staining Representative time-lapse fluorescence microscopy images of h-iNPCE cells during cell migration with RhoA-GTP (red)
          Publications          
001. Baihui (DU20)-penetrating Qubin (GB7) acupuncture on blood-brain barrier integrity in rat intracerebral hemorrhage models via the RhoA/ROCK II/MLC 2 signaling pathway
Animal Model Exp Med. 2024 PMID:38379356
002. FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation
Cell Death Dis. 2024 PMID:38615011
003. Infiltrative vessel co-optive growth pattern induced by IQGAP3 overexpression promotes microvascular invasion in hepatocellular carcinoma
Clin Cancer Res. 2024 PMID:38470497
004. Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines
Brain Behav Immun. 2024 PMID:38042209
005. Balancing act of small GTPases downstream of plexin-A4 signaling motifs promotes dendrite elaboration in mammalian cortical neurons
Sci Signal. 2024 PMID:38227686
006. Tensin-3 is involved in osteogenic versus adipogenic fate of human bone marrow stromal cells
Cell Mol Life Sci. 2023 PMID:37668682
007. Tumoricidal Activity of Simvastatin in Synergy with RhoA Inactivation in Antimigration of Clear Cell Renal Cell Carcinoma Cells
Int J Mol Sci. 2023 PMID:37298689
008. Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents
PLoS Pathog. 2023 PMID:37115795
009. Nogo-A is secreted in extracellular vesicles, occurs in blood and can influence vascular permeability
J Cereb Blood Flow Metab. 2023 PMID:38000040
010. Targeting ASIC1a Promotes Neural Progenitor Cell Migration and Neurogenesis in Ischemic Stroke
Research (Wash D C). 2023 PMID:37275123
011. Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons
J Cell Sci. 2023 PMID:36744839
012. Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity
Neuron. 2023 PMID:36323321
013. The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment
Cell Death Dis. 2023. 2023 PMID:37612265
014. Ogt Deficiency Induces Abnormal Cerebellar Function and Behavioral Deficits of Adult Mice through Modulating RhoA/ROCK Signaling
J Neurosci. 2023 PMID:37225434
015. Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis
J Cell Commun Signal. 2023 PMID: 36477766
016. Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis
Int J Mol Sci. 2023 PMID: 36834937
017. Junctional Force Patterning drives both Positional and Orientational Order in Auditory Epithelia
Research Square. 2023 PMID:
018. CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
Cancer Cell. 2022 PMID:36379207
019. BKM120 alters the migration of doublecortin-positive cells in the dentate gyrus of mice
Pharmacol Res. 2022 PMID:35460881
020. Liquiritigenin alleviates doxorubicin-induced chronic heart failure via promoting ARHGAP18 and suppressing RhoA/ROCK1 pathway
Exp Cell Res. 2022 PMID:34990617
021. Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis
J Cell Commun Signal. 2022 PMID:36284029
022. Cystic fibrosis macrophage function and clinical outcomes after elexacaftor/tezacaftor/ivacaftor
Eur Respir J. 2022 PMID:36265882
023. ARHGEF15 in Sertoli cells contributes to germ cell development and testicular immune privilege
Biol Reprod. 2022 PMID:36001358
024. Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification
Cardiovasc Pathol. 2022 PMID:35074515
025. Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation
Cardiovasc Res. 2022 PMID:34528082
026. IGF2BP2 promotes gastric cancer progression by regulating the IGF1R-RhoA-ROCK signaling pathway
Cell Signal. 2022 PMID:35306138
027. Long-term exposure to low concentrations of MC-LR induces blood-testis barrier damage through the RhoA/ROCK pathway
Ecotoxicol Environ Saf. 2022 PMID:35367887
028. ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42
J Exp Clin Cancer Res. 2022 PMID:35869555
029. Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma
Nat Commun. 2022 PMID:35484119
030. Modulation of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation of Cell-Cell Adhesion
Adv Biol (Weinh). 2021 PMID:33724731
031. MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling
Ann Transl Med. 2021 PMID:34790749
032. Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization.inhibits cell migration and re-epithelialization of non-healing wounds
Commun Biol. 2021 PMID:34145387
033. Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve
Development. 2021 PMID:34086041
034. Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor
Development. 2021 PMID: 33472844
035. ROCK inhibitor attenuates carbon blacks-induced pulmonary fibrosis in mice via Rho/ROCK/NF-kappa B pathway
Environ Toxicol. 2021 PMID:33792148
036. BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis
Front Cell Dev Biol. 2021 PMID:34957122
037. Benzo(a)pyrene Enhanced Dermatophagoides Group 1 (Der f 1)-Induced TGFß1 Signaling Activation Through the Aryl Hydrocarbon Receptor-RhoA Axis in Asthma
Front Immunol. 2021 PMID:33936062
038. Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease
Int J Mol Sci. 2021 PMID:33799579
039. Modulation of proteoglycan receptor regulates RhoA/CRMP2 pathways and promotes axonal myelination
Neurosci Lett. 2021 PMID:34166723
040. Modulation of proteoglycan receptor regulates RhoA/CRMP2 pathways and promotes axonal myelination
Neurosci Lett. 2021 PMID:34166723
041. Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury
Neurotherapeutics. 2021 PMID:33475953
042. The role of daurisoline treatment in hepatocellular carcinoma: Inhibiting vasculogenic mimicry formation and enhancing sensitivity to sorafenib
Phytomedicine. 2021 PMID:34600176
043. MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer
Theranostics. 2021 PMID:33897882
044. Crosstalk Between Abnormal TSHR Signaling Activation and PTEN/PI3K in the Dedifferentiation of Thyroid Cancer Cells
Front Oncol. 2021 PMID:34650915
045. Astrocytes close the critical period for visual plasticity
bioRxiv. 2020 PMID:34210880
046. ANLN Directly Interacts with RhoA to Promote Doxorubicin Resistance in Breast Cancer Cells
Cancer Manag Res. 2020 PMID:33116832
047. Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity
Oncogene. 2020 PMID:31844251
048. Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
Cell Rep. 2020 PMID:32579923
049. QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
Cell Rep. 2020 PMID:33378678
050. Serotonin 5-HT4 receptor boosts functional maturation of dendritic spines via RhoA-dependent control of F-actin
Commun Biol. 2020 PMID:32060357
051. Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis
Dev Cell. 2020 PMID:32428455
052. europeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation
Front Cell Dev Biol. 2020 PMID:33681186
053. Arhgef5 Binds a-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity
Front Mol Neurosci. 2020 PMID:32587503
054. Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafishs
Nat Commun. 2020 PMID:32620775
055. Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis
Neurobiol Dis. 2020 PMID:31931138
056. Acute compressive stress activates RHO/ROCK-mediated cellular processes
Small GTPases. 2020 PMID:29455593
057. Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation
Stem Cells Int. 2020 PMID:32508931
058. Mitigative Effect of Sipjeondaebo-tang on RhoA Activation in Cold-Exposed Vascular Cells
The Journal of Internal Korean Medicine. 2020 PMID:https://www.jikm.or.kr/journal/view.php?doi=10. 22246/jikm. 2020.41.4.553
059. Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathways
Cell Death & Disease,2019 PMID:31601793
060. The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis
Cell Death Dis. 2019 PMID:31171774
061. BKCa compensates impaired coronary vasoreactivity through RhoA/ROCK pathway in hind-limb unweighted rats
FASEB J. 2019 PMID: 31530101
062. The role of sema4D in vasculogenic mimicry formation in non-small cell lung cancer and the underlying mechanisms
Int J Cancer. 2019 PMID: 30374974
063. RhoA/ROCK Signaling Modulates Lineage Commitment of Mesenchymal Stem Cells in Asthma through Lef1
J Allergy Clin Immunol. 2019 PMID:30194990
064. Claudin-2 suppresses GEF-H1.RHOA.and MRTF.thereby impacting proliferation and profibrotic phenotype of tubular cells
J Biol Chem. 2019 PMID:31481470
065. Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia
J Cell Physiol. 2019 PMID:30609027
066. AMPA receptors modulate the reorganization of F-actin in Bergmann glia cells through the activation of RhoA
J Neurochem. 2019 PMID:30589940
067. Inhibition of Notch1 signaling promotes neuronal differentiation and improves functional recovery in spinal cord injury through suppressing the activation of Ras homolog family member A
J Neurochem. 2019 PMID:31339573
068. miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2
JCI Insight. 2019 PMID:31536479
069. Simvastatin pretreatment ameliorates t-PA-induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats
Neuropsychiatr Dis Treat. 2019 PMID:31410004
070. P120-Catenin And Its Phosphorylation On Tyr228 Inhibits Proliferation And Invasion In Colon Adenocarcinoma Cells
Onco Targets Ther. 2019 PMID:32063714
071. Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling
Pathology – Research and Practice. 2019 PMID:30846413
072. 12(S)-Hydroxyeicosatetraenoic acid downregulates monocyte-derived macrophage efferocytosis: New insights in atherosclerosis
Pharmacol Res. 2019 PMID:31028904
073. Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease
Protein Cell. 2019 PMID:31321704
074. Profibrotic epithelial phenotype: a central role for MRTF and TAZ
Sci Rep. 2019 PMID:30867502
075. Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis
Scientific Reports. 2019 PMID:31406143
076. RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia
Am J Physiol Cell Physiol. 2018 PMID:29070491
077. E3 Ubiquitin-Protein Ligase SMURF1 in the Nucleus Accumbens Mediates Cocaine Seeking
Biol Psychiatry. 2018 PMID:30158054
078. Naringin attenuates MLC phosphorylation and NF-?B activation to protect sepsis-induced intestinal injury via RhoA/ROCK pathway
Biomed Pharmacother. 2018 PMID:29635128
079. Inhibition of RhoA reduces propofol-mediated growth cone collapse.axonal transport impairment.loss of synaptic connectivity and behavioural deficits
Br J Anaesth. 2018 PMID:29576115
080. Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart
Cardiovasc Res. 2018 PMID:29444209
081. The Rho GTPase Rnd1 inhibits epithelial–mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target
Cell Death Dis. 2018 PMID:29706627
082. Social Isolation Induces Rac1-Dependent Forgetting of Social Memory
Cell Rep. 2018 PMID:30304669
083. Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration
Front Immunol. 2018 PMID:30254631
084. The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells
J Exp Med. 2018 PMID:29875261
085. Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception
J Neurosci. 2018 PMID:29483280
086. COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway
Mol Med Rep. 2018 PMID:29393423
087. ß-Elemene Enhances GAP-43 Expression and Neurite Outgrowth by Inhibiting RhoA Kinase Activation in Rats with Spinal Cord Injury
Neuroscience. 2018 PMID:29751054
088. MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling
Oncol Lett. 2018 PMID:30008936
089. Anti-Inflammatory Activity in Colon Models Is Derived from Δ9-Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts
Cannabis Cannabinoid Res. 2017 PMID:29082314
090. Effects of chemerin/CMKLR1 in obesity-induced hypertension and potential mechanism
Am J Transl Res. 2017 PMID:28670396
091. The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage
Blood. 2017 PMID:28743719
092. Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3
BMC Complement Altern Med. 2017 PMID:29284478
093. Escort cells generate a dynamic compartment for germline stem cell differentiation via combined Stat and Erk signalling
Development. 2017 PMID:28559239
094. Rho differentially regulates the Hippo pathway by modulating the interaction between Amot and Nf2 in the blastocyst
Development. 2017 PMID:28947533
095. RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos
Dev Biol. 2017 PMID:27836552
096. Myosin 1g Contributes to CD44 Adhesion Protein and Lipid Rafts Recycling and Controls CD44 Capping and Cell Migration in B Lymphocytes
Front Immunol. 2017 PMID:29321775
097. Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma
Genes Dev. 2017 PMID:28887414
098. Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function
Hum Mol Genet. 2017 PMID:29016860
099. The desmoplakin–intermediate filament linkage regulates cell mechanics
Mol Biol Cell. 2017 PMID:28495795
100. Curcumin inhibits growth of human breast cancer cells through demethylation of DLC1 promoter
Mol Cell Biochem. 2017 PMID:27830358
101. Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma
Mol Med Rep. 2017 PMID:28487984
102. Inhibitory effect of Angelica gigas on cold-induced RhoA activation in vascular cells
Mol Med Rep. 2017 PMID:28350093
103. 3D microniches reveal the importance of cell size and shape
Nat Commun. 2017 PMID:29213086
104. Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference
Neuropsychopharmacology. 2017. PMID:28726800
105. EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway
Oncotarget. 2017 PMID:28881620
106. inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide
Pharmacol Res Perspect. 2017 PMID:28971603
107. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary
PLoS Genet. 2017 PMID:28072828
108. RhoA phosphorylation mediated by Rho/RhoA-associated kinase pathway improves the anti-freezing potentiality of murine hatched and diapaused blastocysts
Sci Rep. 2017 PMID:28751650
109. The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia
Sleep Breath. 2017 PMID:28078487
110. Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco-2 cells
United European Gastroenterol J. 2017 PMID:29238589
111. Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency
Am J Respir Crit Care Med. 2016 PMID:26694899
112. Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity
Cell Discov. 2016 PMID:27462462
113. Elongator controls cortical interneuron migration by regulating actomyosin dynamics
Cell Res. 2016 PMID:27670698
114. Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells
Clin Exp Med. 2016 PMID:25596714
115. Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice
Eur J Immunol. 2016 PMID:27188212
116. Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells
Evidence-Based Complementary and Alternative Medicine. 2016 PMID:27651818
117. Thiopurine Prodrugs Mediate Immunosuppressive Effects by Interfering with Rac1 Protein Function
J Biol Chem. 2016 PMID:27189938
118. The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation.
J Bone Miner Res. 2016 PMID:27218883
119. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells
J Cell Sci. 2016 PMID:27231093
120. Alpha 7 nicotinic receptor coupling to heterotrimeric G proteins modulates RhoA activation.cytoskeletal motility.and structural growth
J Neurochem. 2016 PMID:27167578
121. Converging.Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses
J Neurosci. 2016 PMID:27807170
122. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix
Nat Commun. 2016 PMID:27126736
123. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Nature Immunology,2016 PMID:27776107
124. TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure
PLoS One. 2016 PMID:27893804
125. p-Hydroxylcinnamaldehyde induces the differentiation of oesophageal carcinoma cells via the cAMP-RhoA-MAPK signalling pathway
Scientific Reports . 2016 PMID:27501997
126. Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling.
Stem Cells Dev. 2016 PMID:27269634
127. Expression of G Protein-coupled Receptor 56 Is an Unfavorable Prognostic Factor in Osteosarcoma Patients
Tohoku J Exp Med. 2016 PMID:27396430
128. Netrin-1 promotes cell migration and invasion by down-regulation of BVES expression in human hepatocellular carcinoma
Am J Cancer Res. 2015 PMID:26101705
129. Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve
Current Biology. 2015 PMID:26725196
130. Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation
Dev Biol. 2015 PMID:26188246
131. Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation
Development. 2015 PMID:25813538
132. Sodium Ferulate Reduces Portal Pressure Through Inhibition of RhoA/Rho-Kinase and Activation of Endothelial Nitric Oxide Synthase in Cirrhotic Rats
Dig Dis Sci. 2015 PMID:25724163
133. Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease
J Am Soc Nephrol. 2015 PMID:24925721
134. Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex
J Cell Sci. 2015 PMID:26290381
135. Dp63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts
J Mol Cell Cardiol. 2015 PMID:26392029
136. Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage
J Mol Neurosci. 2015 PMID:25896910
137. Kaempferol-3-O-rutinoside from Afgekia mahidoliae promotes keratinocyte migration through FAK and Rac1 activation
J Nat Med. 2015 PMID:25783411
138. A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells
Journal of Natural Medicines. 2015 PMID:26109451
139. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration
Nat Commun. 2015 PMID:26166433
140. Depletion of histone deacetylase 1 inhibits metastatic abilities of gastric cancer cells by regulating the miR-34a/CD44 pathway
Oncology. 2015 PMID:26035691
141. piggyBac Insertional Mutagenesis Screen Identifies a Role for Nuclear RHOA in Human ES Cell Differentiation
Stem Cell Reports,2015 PMID:25866159
142. Cisplatin at Sub-toxic Levels Mediates Integrin Switch in Lung Cancer Cells
Anticancer Research. 2014 PMID:25503138
143. Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases
Biochimica et Biophysica Acta (BBA) – General Subjects. 2014 PMID:24447566
144. The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways
Cell Physiol Biochem. 2014 PMID:24902944
145. MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells
Cytokine. 2014 PMID:25022961
146. Podocyte-specific GLUT4 deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy
Diabetes. 2014 PMID:24101677
147. ARGS5 promotes arterial growth during arteriogenesis
EMBO Mol Med. 2014 PMID:24972930
148. RGS5 promotes arterial growth during arteriogenesis
EMBO Mol Med. 2014 PMID:24972930
149. Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells
Int J Oncol. 2014 PMID:24859471
150. Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours
J Cell Sci. 2014 PMID:24463819
151. Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells
J Cell Sci. 2014 PMID:24610943
152. Triclosan Potentiates Epithelial-To-Mesenchymal Transition in Anoikis-Resistant Human Lung Cancer Cells
PLoS One. 2014 PMID:25329306
153. Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis
Cell Death and Differentiation. 2013 PMID:23645207
154. Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells
Cell Death and Disease,2013 PMID:24113182
155. Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo
Dev Growth Differ. 2013 PMID:23550588
156. Cyclodextrin protects podocytes in diabetic kidney disease
Diabetes. 2013 PMID:23835338
157. N-glycosylation induces collagen triple helix repeat containing 1 (CTHRC1) and drives oral cancer cell migration
J Biol Chem. 2013 PMID:23703614
158. JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
J Cell Biol. 2013 PMID:24368807
159. Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway
J Neurochem. 2013 PMID:23895422
160. MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
PLoS One. 2013 PMID:23894602
161. Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats
Am J Physiol Heart Circ Physiol. 2012 PMID:22505643
162. WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization
Am J Physiol Renal Physiol. 2012 PMID:21900451
163. Invadopodia and rolling-type motility are specific features of highly invasive p190(bcr-abl) leukemic cells
Eur J Cell Biol. 2012 PMID:22717125
164. LINGO-1.a transmembrane signaling protein.inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions
J Biol Chem. 2012 PMID:22514275
165. Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth
J Biol Chem. 2012 PMID:22923615
166. A role for myosin IXb.a motor-RhoGAP chimera.in epithelial wound healing and tight junction regulation
Mol Biol Cell. 2012 PMID:22573889
167. Endothelial PI3K-C2à.a class II PI3K.has an essential role in angiogenesis and vascular barrier function
Nat Med. 2012 PMID:22983395
168. C3 Peptide Promotes Axonal Regeneration and Functional Motor Recovery after Peripheral Nerve Injury
Neurotherapeutics. 2012 PMID:21866396
169. The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1
Oncogene. 2012 PMID:22139079
170. ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA
PLoS One. 2012 PMID:22558255
171. Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation
Proc Natl Acad Sci U S A. 2012 PMID:22307599
172. Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
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