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Orai1-L1 pAb

Anti-Orai1-L1 Rabbit Polyclonal Antibody
5/5

$219.00

Cat.#:  21001

   Size:   100 μl

In Stock

          Product Description          

Orai1-L1 Polyclonal Antibody

Cat. #:  21001
Gene Symbol:  Orai1
Description:   Anti-Orai1-L1 Rabbit Polyclonal Antibody
Background:   Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combined immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.
Immunogen:   A peptide from the extracellular loop 1 region of human Orai1
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA:      1:1000-1:5000,
WB:          1:1000-1:2000,
IHC:          1:100-1:200
Concentration:   
Host Species:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   IgG
Purity:   Immunogen affinity purified
Preservative: No
Constituents:    50 mM NaHCO3-Glycine, 0.15M NaCl, pH7.4
Species Reactivity:  Orai1-L1 antibody recognizes Orai1 from human and mouse. It may also recognize Orai2 and Orai3.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

Western blot analysis of Orai1 protein. Human Orai1 plasmid DNA was transiently transfected into HEK-293 cells. Whole-cell lysate was used for western blot in the absence (lane 1) or presence (lane 2) of antigen peptide.


Immunohistochemistry:

Immunohistochemistry of endogenous Orai1 in NIH3T3 cells showing the plasma membrane staining.