| Catalog Number: 26005 | | Gene Symbol: RAC1 | | Description: Anti-Rac1 Mouse Monoclonal Antibody | | Background: Small GTPases are a super-family
of cellular signaling regulators. Rac belongs to
the Rho sub-family of GTPases that regulate cell
motility, cell division, and gene transcription. In
mammals, there are three Rac genes: Rac1, Rac2
and Rac3. GTP binding increases the activity of
Rac, and the hydrolysis of GTP to GDP renders it
inactive. GTP hydrolysis is aided by GTPase
activating proteins (GAPs), while exchange of
GDP for GTP is facilitated by guanine nucleotide
exchange factors (GEFs). | | Immunogen: Recombinant full length protein of
Rac1 | | Applications: ELISA, WB, IHC | | Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:1000-1:2000 | | Concentration: 1 mg/ml | | Host: mouse | | Format: Liquid | | Clonality: Monoclonal | | Isotype: IgG | | Purity: Purified from ascites | | Storage buffer: | | Preservative: no | | Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species | | Species Reactivity: Rac1 antibody recognizes Rac1 from vertebrates. | | Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles | Download Datasheet:  | | Western blot: |
 | Western blot analysis of Rac1 proteins. MEF
whole-cell lysate was used for western blots.
The monoclonal anti-Rac1 antibody was
pre-incubated without (lane 1) or with (lane 2)
the antigen protein (Rac1) to show the specificity. |
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