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G protein Polyclonal antibody

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Anti Ric-8A Mouse Monoclonal Antibody

Price2800.00
BrandNewEastBio   
Place of OriginUSA
Catalog Number26071
ImmunogenMouse
Size100μl
Technical InformationView technical data
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  • Summary

    Ric-8A [26071]
    [100 µL]

    Catalog Number:  26071
    Gene Symbol:  RIC8A
    Description:   Anti Ric8A Mouse Monoclonal Antibody
    Background:   Ric-8A (Resistance to Inhibitors of Cholinesterase-8A) interacts with Gαo, Gαi, Gαq and Gα13, but not Gαs, proteins. Mammalian Ric-8A protein is a guanine nucleotide exchange factor for Gαq, Gαi, Gαo, Gα12, Gα13, but not for Gαs. C. elegans Ric8 (also named Synembryn) is required for proper asymmetric division of 1-cell-stage embryos. Ric8 is required for the generation of substantial pulling forces on astral microtubules.
    Immunogen:   A synthetic peptide near the C-terminus of Ric-8A, human origin.
    Applications:   ELISA, WB, IHC, IP
    Recommended Dilutions:   
    ELISA: 1:100-1:5000 
    WB: 1:100-1:2000 
    IHC: 1:50-1:100
    Concentration:   1 mg/ml
    Host:   mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   IgG
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Ric-8A antibody recognizes Ric-8A from vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
    Download Datasheet:  
    Western blot:  
    Western blot analysis of Ric-8A proteins. Whole-cell lysate of HeLa cells was blotted with anti Ric-8A monoclonal antibody (Cat. #26071).
    Publications:
    1.  Atypical Protein Kinase Cλ is Critical for Growth Factor Receptor-Induced Dorsal Ruffle Turnover and Cell Migration
        J Biol Chem. 2013 Nov 15;288(46):32827-36