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G Protein Monoclonal Antibodies

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Anti RheB Rabbit Polyclonal Antibody

Price$219.00
BrandNewEastBio   
Place of OriginUSA
Catalog Number21098
ImmunogenRabbit
Size100μl
Technical InformationView technical data
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  • Summary

    RheB [21098]
    [100 µL]


    Catalog Number:  21098
    Gene Symbol:  RHEB
    Description:   Anti RheB Rabbit Polyclonal Antibody
    Background:   Small GTPases are a super-family of cellular signaling regulators. RheB is a member of the Ras-superfamily GTPases. RheB has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR).
    Immunogen:    A synthetic peptide from the C-terminal region of human RheB
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:100-1:1000 
    IHC: 1:100-1:1000
    Concentration:   0.2 mg/ml
    Host:   Rabbit
    Format:   Liquid
    Clonality:   Polyclonal
    Isotype:   IgG
    Purity:   Purified from serum
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Anti-RheB antibody recognizes RheB of vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
    Download Datasheet:  
    Western blot:  
    Western blot analysis of RheB proteins. Whole-cell lysate of HEK-293T cells was used for western blot with the polyclonal anti RheB antibody (Cat # 21098).



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    Publications:
    1.  Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
        Cancer Res. 2014 Feb 15;74(4):1067-78
    2.  SynGAP Regulates Protein Synthesis and Homeostatic Synaptic Plasticity in Developing Cortical Networks
        PLoS One. 2013 Dec 31;8(12):e83941