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Antibodies for Proto-oncogene


Anti GRB7 Rabbit Polyclonal Antibody

Place of OriginUSA
Catalog Number21218
Size100 μl
Technical InformationView technical data
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  • Summary

    GRB7 [21218]
    [100 µL]

    Catalog Number:  21218
    Gene Symbol:  GRB7
    Description:   Anti GRB7 Rabbit Polyclonal Antibody
    Background:   Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in breast cancers. Grb7 is over-expressed in testicular germ cell tumors, esophageal cancers, and gastric cancers. There are clues that it involved in cell migration and metastatic progression of human esophageal carcinomas.
    Immunogen:   A synthetic peptide from the C-terminus of GRB7 protein, human origin.
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:250-1:1000 
    IHC: 1:50-1:100
    Concentration:   0.5 mg/ml
    Host:   Rabbit
    Format:   Liquid
    Clonality:   Polyclonal
    Purity:   Purified from serum
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Anti GRB7 rabbit polyclonal antibody recognizes GRB7 from vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles.
    Download Datasheet:  
    Western blot:  
    Western blot analysis of GRB7 proteins. Whole-cell lysate of MEF cells was blotted with anti GRB7 polyclonal antibody (Cat. #26071).

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